Technetium-99m sestamibi scintigraphy in monitoring patients with multiple myeloma.

نویسندگان

  • A M Pinto
  • C Califano
  • F Di Gennaro
  • A De Renzo
  • L Catalano
  • L Pace
چکیده

1. Risdall RJ, Brunning RD, Hernandez JI, Gordon DH. Bacteria-associated hemophagocytic syndrome. Cancer 1984; 54:2968-72. 2. Boruchoff SE, Woda BA, Pihan GA, Durbin WA, Burstein D, Blacklow NR. Parvovirus B19-associated hemophagocytic syndrome. Arch Intern Med 1990; 150:897-9. 3. Su IJ, Hsu YH, Lin MT, Cheng AL, Wang CH, Weiss LM. Epstein-Barr virus-containing T-cell lymphoma presents with hemophagocytic syndrome mimicking malignant histiocytosis. Cancer 1993; 72:2019-27. 4. Chen RL, Lin KH, Lin DT, et al. Immunomodulation treatment for childhood virus-associated haemophagocytic lymphohistiocytosis. Br J Haematol 1995; 89:282-90. 5. Chen JS, Lin KH, Lin DT, Chen RL, Jou ST, Su IJ. Longitudinal observation and outcome of nonfamilial childhood haemophagocytic syndrome receiving etoposide-containing regimens. Br J Haematol 1998; 103:756-62. 6. Okuda T, Yumoto Y. Subacute necrotizing lymphadenitis with a clinical course mimicking virus-associated hemophagocytic syndrome. Rinsho Ketsueki 1994; 35:689-93. 7. Yufu Y, Matsumoto M, Miyamura T, Nishimura J, Nawata H, Ohshima K. Parvovirus B19-associated haemophagocytic syndrome with lymphadenopathy resembling histiocytic necrotizing lymphadenitis (Kikuchi's disease). Br J Haematol 1997; 96:868-71. 8. Ambruso DR, Hays T, Zwartjes WJ, Tubergen DG, Favara BE. Successful treatment of lymphohistiocytic reticulosis with phagocytosis with epipodophyllotoxin VP 16-213. Cancer 1980; 45:2516-20.

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منابع مشابه

Technetium-99m-sestamibi scintigraphy in multiple myeloma and related gammopathies: a useful tool for the identification and follow-up of myeloma bone disease.

BACKGROUND AND OBJECTIVES Technetium-99m 2-methoxy-isobutyl-isonitrile ((99m)Tc-sestamibi) has recently been proposed as a potential tracer in patients with multiple myeloma (MM), as its increased uptake in the bone marrow has been reported as indicator of myeloma activity. We evaluated the role of (99m)Tc-sestamibi scintigraphy in the detection of myeloma bone disease in MM and related gammopa...

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Technetium 99m sestamibi in multiple myeloma.

bone involvement. Destruction is mediated through normal osteoclasts, which respond to local osteoclast-activating microenvironment [7]. Technetium-99m 2methoxyisobutylisonitrile (TC-99m MIBI) is a lipophilic agent that accumulates within living malignant cells due to the higher transmembrane electrical potential as a consequence of the higher metabolic rate than in the surrounding normal cells...

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Multiple myeloma in a patient with suspected hyperparathyroidism

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of terminally differentiated plasma cells. Imaging modalities which allow the recognition of the effects of myeloma cells on the skeletal system have been utilized for a long time. Herein, we represent a patient with generalized osteoporosis and hypercalcemia, who was referred for parathyroid scan, in whom the widespread bone marrow techne...

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Value of tc99m (V) dmsa compared to tc99m Mibi in Evaluation of Bone and Bone Marrow Lesions in Patients with Multiple Myeloma

Bone scintigraphy has some limitations in detecting bone lesions at the time of diagnosis since Tc99m MDP scintigraphy does not trace lesions lacking osteoblastic activity3. Tc99m Sestamibi (MIBI) has been proposed as a potential tracer in patients with multiple myeloma, as its increased uptake in the bone marrow has been reported as an indicator of myeloma activity4. It has been suggested to b...

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Detection of focal myeloma lesions by technetium-99m-sestaMIBI scintigraphy.

BACKGROUND AND OBJECTIVE The tracer tachnetium-99m-2-methoxy-isobutyl-isonitrile (Tc99m-sestaMIBI) has recently been shown to concentrate in some neoplastic tissues, including myeloma. We investigated the diagnostic capacity and limits of this procedure in tracing focal myeloma lesions, and compared them with those of conventional radiological procedures (Xr). DESIGN AND METHODS We studied 55...

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Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?

Background: Bone lesion in multiple myeloma (MM) is most commonly presented as a lytic lesion in this disease. Determination of extent of bone lesions in MM is necessary to follow-up the patients. Whole body bone scan with 99m, Tc-methylene diphosphonate (MDP) has a lower sensitivity than other modalities. Methods: From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran ...

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عنوان ژورنال:
  • Haematologica

دوره 85 9  شماره 

صفحات  -

تاریخ انتشار 2000